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PROZE
September 19, 2019
SANBACTACEF-250
September 19, 2019
SANBACTACEF-1000
| Brad Name | Sanbactacef-1000 |
| Composition | Ceftriaxone 1000 mg Injections |
Description
Ceftriaxone 1000 mg Injection
Ceftriaxone is used to treat a wide variety of bacterial infections. Ceftriaxone belongs to a class of drugs known as cephalosporin antibiotics. It works by stopping the growth of bacteria.
Ceftriaxone is not recommended for use in newborns with high blood bilirubin levels and premature infants due to increased risk of side effects. Ask the doctor or pharmacist for details.
Ceftriaxone may also be used before dental procedures in people with certain heart conditions (such as artificial heart valves) to help prevent serious infection of the heart (bacterial endocarditis).
Dosage
Adult and Pediatric Dosage Forms and Strengths
Injectable solution
- 1 g/50 mL
- 2 g/50mL
Powder for injection
- 250 mg
- 500 mg
- 1 g
- 2 g
- 10 g (adult only)
- 100 g (adult only)
Precautions
Warnings
This medication contains ceftriaxone. Do not take Rocephin if you are allergic to ceftriaxone or any ingredients contained in this drug.
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.
Contraindications
- Documented hypersensitivity; hyperbilirubinemic neonates, particularly those who are premature; neonates under 28 days if they receive calcium-containing intravenous (IV) products.
- Intravenous administration of ceftriaxone solutions containing lidocaine.
- Lidocaine contraindications if lidocaine solution used as solvent with ceftriaxone for intramuscular injection.
Side effects
Common side effects of ceftriaxone include:
- Injection site reactions (swelling, redness, pain, a hard lump, or soreness)
- Eosinophilia
- Increased blood platelets (thrombocytosis)
- Diarrhea
- Elevated liver transaminases
- Low white blood cell count (leukopenia)
- Rash
- Increased blood urea nitrogen (BUN)
- Pain
Less common side effects of ceftriaxone include:
- Agranulocytosis
- Anemia
- Basophilia
- Blood in the urine
- Bronchospasm
- Changes in taste
- Chills
- Dizziness
- Excess sweating
Drug interaction
If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.
Ceftriaxone has no known severe interactions with other drugs.
Severe interactions of ceftriaxone include:
- calcium acetate
- calcium carbonate
- calcium chloride
- calcium citrate
- calcium gluconate
Serious interactions of ceftriaxone include:
- argatroban
- BCG vaccine live
- bivalirudin
- cholera vaccine
- dalteparin
- enoxaparin
Moderate interactions of ceftriaxone include:
- bazedoxifene/conjugated estrogens
- chloramphenicol
- demeclocycline
- dienogest/estradiol valerate
- doxycycline
- erythromycin base
- erythromycin ethylsuccinate
Mild interactions of ceftriaxone include:
- choline magnesium trisalicylate
- furosemide
- rose hips
- willow bark